Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 5/20 | 0.47 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | USP7 | Q93009 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29028719 | 0.88 | MAPT (0.46) | MPOKDM4EESR2MAPTMEN1 | |
| SCHEMBL29028724 | 0.88 | SMN1; SMN2 (0.46) | MPOESR2MAPTMEN1KMT2A | |
| SCHEMBL29028680 | 0.88 | NPC1 (0.43) | MPOKDM4EESR2MAPTMEN1 | |
| SCHEMBL29028787 | 0.88 | MAPT (0.46) | MPOKDM4EESR2MAPTMEN1 | |
| SCHEMBL29028789 | 0.86 | MPO (0.39) | MPOKDM4EESR2MAPTMEN1 | |
| SCHEMBL30473327 | 0.84 | MEN1 (0.41) | MPOKDM4EMAPTMEN1KMT2A | |
| SCHEMBL29028702 | 0.84 | RAB9A (0.47) | MPOKDM4EESR2MAPTMEN1 | |
| SCHEMBL29028782 | 0.84 | LMNA (0.51) | MPOMAPTKMT2AALDH1A1HSD17B10 | |
| SCHEMBL29028781 | 0.84 | MPO (0.47) | MPOMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL29028711 | 0.84 | MPO (0.55) | MPOKDM4EESR2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332851-A | Cyanomethyl phenyl indazole compound and preparation method thereof | 河南中医药大学 | 2023-06-27 | — | — | CN | disclosed |