SCHEMBL29028798

SCHEMBL29028798

O=C(CCCCCCCCCCCCc1ccccc1)OCC(O)CO

nearest known ligand 0.70

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LPAR1 Q92633 7/20 0.70
ADRB2 P07550 1/20 0.60
ADRB1 P08588 1/20 0.60
ADRB3 P13945 1/20 0.60
KDM4E B2RXH2 1/20 0.57
DUSP3 P51452 1/20 0.57
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
LMNA P02545 1/20 0.57
MGLL Q99685 1/20 0.54
CNR2 P34972 3/20 0.54
MAPT P10636 1/20 0.53
RXFP1 Q9HBX9 1/20 0.53
DGKA P23743 1/20 0.50
TRPA1 O75762 1/20 0.49
TDP1 Q9NUW8 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11293636 1.00 LPAR1 (0.70) LPAR1ADRB2ADRB1ADRB3KDM4E
SCHEMBL1983179 0.94 ADRB2 (0.66) LPAR1ADRB2ADRB1ADRB3KDM4E
Phenylbutanoic Acid SCHEMBL406962 0.90 ADRB2 (0.62) LPAR1ADRB2ADRB1ADRB3KDM4E
Phenylbutanoic Acid SCHEMBL28794522 0.87 HDAC3 (0.61) LPAR1ADRB2ADRB1ADRB3KDM4E
SCHEMBL9463643 0.86 LPAR1 (0.71) LPAR1ADRB2ADRB1ADRB3KMT2A
SCHEMBL11877761 0.81 KMT2A (0.55) LPAR1ADRB2ADRB1ADRB3KDM4E
SCHEMBL8332902 0.81 LMNA (0.82) LPAR1KDM4EDUSP3MEN1KMT2A
SCHEMBL839526 0.81 LMNA (0.82) LPAR1KDM4EDUSP3MEN1KMT2A
SCHEMBL20624 0.81 LMNA (0.82) LPAR1KDM4EDUSP3MEN1KMT2A
SCHEMBL380177 0.81 LMNA (0.82) LPAR1KDM4EDUSP3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116332765-B Alkanoate compound and preparation method and application thereof 江西省药品检验检测研究院 2023-08-04 CN claimed
CN-116332765-A Alkanoate compound and preparation method and application thereof 江西省药品检验检测研究院 2023-06-27 CN claimed
CN-116332765-B Alkanoate compound and preparation method and application thereof 江西省药品检验检测研究院 2023-08-04 CN disclosed
CN-116332765-A Alkanoate compound and preparation method and application thereof 江西省药品检验检测研究院 2023-06-27 CN disclosed