SCHEMBL2902917

SCHEMBL2902917

Clc1cccc(Cl)c1Oc1cc[c]cn1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
RARG P13631 1/20 0.35
KMT2A Q03164 2/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8131243 0.81 ALDH1A1 (0.42) KMT2AKDM4ECYP1A2CYP2C19NPSR1
SCHEMBL693585 0.81 KMT2A (0.49) KMT2ALMNA
SCHEMBL2751987 0.79 SLC6A2 (0.33) KMT2A
SCHEMBL2750651 0.76 SMN1; SMN2 (0.50) KMT2AKDM4ELMNA
SCHEMBL2895213 0.76 L3MBTL1 (0.38)
SCHEMBL693084 0.75 CYP1A2 (0.50) LMNACYP1A2CYP2C19
SCHEMBL2901814 0.73 L3MBTL1 (0.44) KMT2AKDM4ELMNACYP1A2CYP2C19
SCHEMBL2895207 0.72 HAO1 (0.47) KMT2AKDM4E
SCHEMBL28165762 0.72 KDM4E (0.47) RARGKMT2AKDM4ELMNACYP1A2
SCHEMBL315475 0.72 ALDH1A1 (0.43) KMT2AKDM4ECYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100305124-A1 Acylated Aminopyridine and Aminopyridazine Insecticides BAYER CROPSCIENCE AG (DE) 2010-12-02 US disclosed
EP-2236505-A1 Acylated aminopyridines and pyridazines as insecticides Bayer CropScience AG (DE) 2010-10-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100305124-A1 Acylated Aminopyridine and Aminopyridazine Insecticides AAAS, DDT, QDPR RARG 3942/4885KMT2A 412/4885KDM4E 762/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.