Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 5/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290106 | 0.86 | CTSC (0.46) | CTSCKCNH2 | |
| SCHEMBL290462 | 0.82 | CTSC (0.46) | CTSCKCNH2 | |
| SCHEMBL2892493 | 0.82 | CTSC (0.63) | CTSCKCNH2CTSK | |
| SCHEMBL290293 | 0.80 | CTSC (0.50) | CTSCKCNH2CTSKBRD4 | |
| SCHEMBL290319 | 0.79 | CTSC (0.42) | CTSCKCNH2CTSK | |
| SCHEMBL299100 | 0.78 | CTSC (0.49) | CTSCKCNH2 | |
| SCHEMBL290245 | 0.78 | CTSS (0.39) | CTSK | |
| SCHEMBL289727 | 0.76 | CTSC (0.54) | CTSCCTSK | |
| SCHEMBL290265 | 0.76 | CTSC (0.34) | CTSCKCNH2CTSK | |
| SCHEMBL290665 | 0.76 | CTSC (0.34) | CTSCKCNH2CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427445-A1 | SUBSTITUTED 1-CYANOETHYLHETEROCYCLYLCARBOXAMIDE COMPOUNDS 750 | AstraZeneca AB (SE) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128324-A1 | SUBSTITUTED 1-CYANOETHYLHETEROCYCLYLCARBOXAMIDE COMPOUNDS 750 | ASTRAZENECA AB (SE) | 2010-11-11 | — | — | WO | disclosed |