Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290319 | 0.81 | CTSC (0.42) | CTSCCTSK | |
| SCHEMBL290265 | 0.81 | CTSC (0.34) | CTSCCTSK | |
| SCHEMBL290665 | 0.81 | CTSC (0.34) | CTSCCTSK | |
| SCHEMBL288985 | 0.80 | MMP1 (0.41) | CTSCCTSK | |
| SCHEMBL290023 | 0.80 | CTSC (0.45) | CTSC | |
| SCHEMBL2888765 | 0.80 | CTSC (0.78) | CTSCCTSK | |
| SCHEMBL290245 | 0.79 | CTSS (0.39) | CTSK | |
| SCHEMBL290311 | 0.79 | MMP12 (0.44) | CTSC | |
| SCHEMBL289589 | 0.78 | RORC (0.37) | CTSC | |
| SCHEMBL290109 | 0.78 | CTSC (0.52) | CTSCCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427445-A1 | SUBSTITUTED 1-CYANOETHYLHETEROCYCLYLCARBOXAMIDE COMPOUNDS 750 | AstraZeneca AB (SE) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128324-A1 | SUBSTITUTED 1-CYANOETHYLHETEROCYCLYLCARBOXAMIDE COMPOUNDS 750 | ASTRAZENECA AB (SE) | 2010-11-11 | — | — | WO | disclosed |