Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.50 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.39 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KDM5C | P41229 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL7860504 | 0.94 | LMNA (0.56) | EGLN1LMNAALKBH5SUCNR1GLA | |
| Succinic Acid SCHEMBL27874699 | 0.94 | LMNA (0.56) | EGLN1LMNAALKBH5SUCNR1GLA | |
| Levulinic Acid SCHEMBL2634413 | 0.87 | LMNA (0.67) | EGLN1LMNAALKBH5SUCNR1GLA | |
| Succinic Acid SCHEMBL28079111 | 0.85 | LMNA (0.60) | EGLN1LMNAALKBH5SUCNR1GLA | |
| Butyric Acid SCHEMBL5740470 | 0.84 | FFAR3 (0.65) | EGLN1LMNAALKBH5SUCNR1GLA | |
| Tetrahydrofuran SCHEMBL27415023 | 0.83 | FFAR3 (0.56) | EGLN1LMNAALKBH5SUCNR1GLA | |
| Propionic Acid SCHEMBL28145772 | 0.83 | FFAR3 (0.56) | EGLN1LMNAALKBH5SUCNR1GLA | |
| Adipic Acid SCHEMBL28032942 | 0.83 | LMNA (0.61) | LMNAGLAALDH1A1HSD17B10OR51E2 | |
| Adipic Acid SCHEMBL1638937 | 0.83 | LMNA (0.61) | LMNAGLAALDH1A1HSD17B10OR51E2 | |
| Tetrahydrofuran SCHEMBL3874046 | 0.82 | ALDH1A1 (0.50) | LMNAGLASLC15A2ALDH1A1FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114133539-B | Degradable copolymer and preparation method thereof | 浙江糖能科技有限公司 | 2023-05-30 | — | — | CN | disclosed |