Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 7/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28767432 | 0.93 | CA2 (0.42) | CA2CA1LMNAHSD17B10SLC1A2 | |
| SCHEMBL28731369 | 0.93 | CA2 (0.42) | CA2CA1LMNAHSD17B10SLC1A2 | |
| SCHEMBL29652036 | 0.88 | LMNA (0.42) | CA2CA1LMNAHSD17B10SLC1A3 | |
| SCHEMBL15968120 | 0.85 | CPB2 (0.37) | CA2CA1LMNAHSD17B10TSHR | |
| SCHEMBL2348467 | 0.83 | LMNA (0.32) | LMNAHSD17B10TSHR | |
| SCHEMBL15968437 | 0.83 | CPB2 (0.40) | LMNAHSD17B10TSHRNFKB1 | |
| SCHEMBL8906124 | 0.82 | CA2 (0.41) | CA2CA1MAPK1SLC1A3SLC1A2 | |
| SCHEMBL11042718 | 0.81 | CYP4F2 (0.35) | LMNAHSD17B10TSHRTDP1 | |
| SCHEMBL14877272 | 0.80 | KISS1R (0.41) | LMNAHSD17B10TSHR | |
| SCHEMBL5100758 | 0.80 | GABRR1 (0.35) | LMNAHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116406359-A | Bicyclo [1.1.1] pentanes for the treatment and prevention of hepatitis B virus infection | 豪夫迈·罗氏有限公司 | 2023-07-07 | — | — | CN | disclosed |