Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | GFER | P55789 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL806437 | 0.87 | GAA (0.76) | ALDH1A1MAPTMAPK1GAAGFER | |
| SCHEMBL30434229 | 0.87 | GAA (0.76) | ALDH1A1MAPTMAPK1GAAGFER | |
| SCHEMBL7564170 | 0.87 | GAA (0.76) | ALDH1A1MAPTMAPK1GAAGFER | |
| SCHEMBL29031227 | 0.85 | MAPK1 (0.57) | ALDH1A1MAPTMAPK1GAAGFER | |
| SCHEMBL790294 | 0.81 | GAA (0.86) | ALDH1A1MAPTMAPK1GAAGFER | |
| SCHEMBL8752441 | 0.80 | ALDH1A1 (0.72) | ALDH1A1MAPTMAPK1GAAGFER | |
| SCHEMBL6741160 | 0.77 | ALDH1A1 (0.67) | ALDH1A1MAPTMAPK1GAAGFER | |
| SCHEMBL11158903 | 0.77 | ALDH1A1 (1.00) | ALDH1A1MAPTMAPK1GAAGFER | |
| SCHEMBL1471967 | 0.77 | FFAR1 (0.88) | ALDH1A1MAPTMAPK1GAAGFER | |
| SCHEMBL32679643 | 0.77 | GAA (0.78) | ALDH1A1MAPTMAPK1GAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999148-B | N- (4- (substituted sulfonyl amino) phenyl) sulfonamide compound and application thereof | 浙江省中医药研究院 | 2023-06-06 | — | — | CN | disclosed |
| CN-113999148-A | N- (4- (substituted sulfonyl amino) phenyl) sulfonamide compound and application thereof | 浙江省中医药研究院 | 2022-02-01 | — | — | CN | disclosed |