SCHEMBL806437

SCHEMBL806437

COc1ccc(S(=O)(=O)Nc2ccc(C)cc2)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.76
MAPK1 P28482 2/20 0.76
LMNA P02545 2/20 0.76
ALDH1A1 P00352 5/20 0.69
PKM P14618 2/20 0.69
FFAR1 O14842 1/20 0.69
PGR P06401 1/20 0.69
MAPT P10636 3/20 0.66
CYP19A1 P11511 1/20 0.66
SMN1; SMN2 Q16637 2/20 0.64
KDM4E B2RXH2 1/20 0.64
MEN1 O00255 1/20 0.64
BLM P54132 1/20 0.64
KMT2A Q03164 1/20 0.64
TDP1 Q9NUW8 1/20 0.64
GFER P55789 1/20 0.64
FFAR4 Q5NUL3 2/20 0.64
GABRG2 P18507 1/20 0.64
GABRB3 P28472 1/20 0.64
GABRA3 P34903 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30434229 1.00 GAA (0.76) GAAMAPK1LMNAALDH1A1PKM
SCHEMBL7564170 1.00 GAA (0.76) GAAMAPK1LMNAALDH1A1PKM
SCHEMBL790294 0.93 GAA (0.86) GAAMAPK1LMNAALDH1A1PKM
SCHEMBL32679643 0.88 GAA (0.78) GAAMAPK1LMNAALDH1A1PKM
SCHEMBL1471967 0.88 FFAR1 (0.88) GAAMAPK1LMNAALDH1A1FFAR1
SCHEMBL29031237 0.87 ALDH1A1 (0.62) GAAMAPK1LMNAALDH1A1PKM
SCHEMBL2005010 0.87 CA12 (0.81) GAAMAPK1LMNAALDH1A1PKM
SCHEMBL21962871 0.86 ALDH1A1 (0.66) GAAMAPK1LMNAALDH1A1MAPT
SCHEMBL29031235 0.86 PGR (0.85) GAAMAPK1LMNAALDH1A1PKM
SCHEMBL2240982 0.85 LMNA (0.73) GAAMAPK1LMNAALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0610653-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1997-04-16 EP claimed
US-5444036-A Arylsulfonylureido compound, acetoacetanilide compound, sulfonamide derivative; storage stability NEW OIL PAPER CO., LTD. (JP) 1995-08-22 US claimed
EP-0610653-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-08-17 EP claimed
WO-2023073115-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2023-05-04 WO disclosed
CN-106008288-A Benzsulfamide compound and application thereof 西北农林科技大学 2016-10-12 CN disclosed
US-9212134-B2 Inhibitors of viral entry into mammalian cells MICROBIOTIX, INC. (US) 2015-12-15 US disclosed
WO-2012037119-A2 INHIBITORS OF VIRAL ENTRY INTO MAMMALIAN CELLS MICROBIOTIX, INC. (US) 2012-03-22 WO disclosed
EP-0610653-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1997-04-16 EP disclosed
US-5444036-A Arylsulfonylureido compound, acetoacetanilide compound, sulfonamide derivative; storage stability NEW OIL PAPER CO., LTD. (JP) 1995-08-22 US disclosed
EP-0610653-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-08-17 EP disclosed