Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30342993 | 0.89 | ALDH1A1 (0.43) | MAPTTHRATHRBTDP1NPC1 | |
| SCHEMBL27170273 | 0.88 | THRA (0.41) | MAPTKMT2AMEN1THRATHRB | |
| SCHEMBL12467087 | 0.88 | PARP15 (0.51) | MAPTTHRATHRBNPC1RAB9A | |
| SCHEMBL5467355 | 0.85 | MAPT (0.41) | MAPTTHRATHRBMAOBMAOA | |
| SCHEMBL5234224 | 0.82 | MAPT (0.50) | MAPTKMT2AMEN1THRATHRB | |
| SCHEMBL19717306 | 0.79 | MAPT (0.69) | MAPTKMT2AMEN1TDP1NPC1 | |
| SCHEMBL7517952 | 0.79 | ADRB2 (0.41) | MAPTKMT2AMEN1TDP1NPC1 | |
| SCHEMBL8902098 | 0.79 | THRA (0.53) | MAPTKMT2AMEN1THRATHRB | |
| SCHEMBL862088 | 0.79 | PPARG (0.48) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL16568445 | 0.79 | PTPN2 (0.39) | MAPTNPC1RAB9AHSP90AA1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116438174-A | Compounds and their use as MIF inhibitors | 南京艾美斐生物医药科技有限公司 | 2023-07-14 | — | — | CN | disclosed |
| EP-4168399-A1 | COMPOUNDS AND THEIR USES AS MIF INHIBITORS | Nanjing Immunophage Biotech Co., Ltd. (CN) | 2023-04-26 | — | — | EP | disclosed |