SCHEMBL2903333

SCHEMBL2903333

CC(C)C(=O)Nc1c[c]ccc1Cl

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
ALDH1A1 P00352 2/20 0.48
LMNA P02545 2/20 0.46
MDM4 O15151 2/20 0.45
TP53 P04637 2/20 0.45
HTT P42858 2/20 0.43
CETP P11597 1/20 0.42
GRM4 Q14833 1/20 0.40
MDM2 Q00987 1/20 0.40
GAA P10253 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
KDM4E B2RXH2 2/20 0.38
RECQL P46063 1/20 0.38
KCNQ2 O43526 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22683489 0.87 MDM4 (0.45) MEN1KMT2AALDH1A1LMNAMDM4
SCHEMBL1452105 0.84 MDM4 (0.49) MEN1KMT2AALDH1A1LMNAMDM4
SCHEMBL2900761 0.83 MDM4 (0.47) MEN1KMT2AALDH1A1LMNAMDM4
SCHEMBL2894903 0.81 ALDH1A1 (0.46) MEN1KMT2AALDH1A1TP53HTT
SCHEMBL1477556 0.80 MDM4 (0.45) MEN1KMT2AALDH1A1LMNAMDM4
SCHEMBL27771714 0.80 HPGD (0.49) MEN1KMT2ALMNAHTTKDM4E
SCHEMBL1447712 0.78 MDM4 (0.46) MEN1KMT2AALDH1A1LMNAMDM4
SCHEMBL2902879 0.78 HTT (0.46) KMT2AALDH1A1MDM4TP53HTT
SCHEMBL2897809 0.77 MEN1 (0.48) MEN1KMT2AALDH1A1LMNAHTT
SCHEMBL14254815 0.76 LMNA (0.62) MEN1KMT2AALDH1A1LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100305124-A1 Acylated Aminopyridine and Aminopyridazine Insecticides BAYER CROPSCIENCE AG (DE) 2010-12-02 US disclosed
EP-2236505-A1 Acylated aminopyridines and pyridazines as insecticides Bayer CropScience AG (DE) 2010-10-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100305124-A1 Acylated Aminopyridine and Aminopyridazine Insecticides AAAS, DDT, QDPR MEN1 2671/4885KMT2A 412/4885ALDH1A1 551/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.