Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22747549 | 0.90 | MTNR1A (0.53) | PTGS2MTNR1AMTNR1BPDE4BMEN1 | |
| SCHEMBL29033496 | 0.90 | MTNR1A (0.53) | PTGS2MTNR1AMTNR1BPDE4BMEN1 | |
| SCHEMBL22161378 | 0.88 | TUBB4A (0.49) | PTGS2MTNR1AMTNR1BPDE4BMEN1 | |
| SCHEMBL29033499 | 0.83 | CCNC (0.50) | MTNR1AMTNR1BPDE4BMEN1KMT2A | |
| SCHEMBL18932674 | 0.79 | KMT2A (0.66) | PDE4BMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL29033534 | 0.77 | MAPT (0.47) | PDE4BMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL29033515 | 0.76 | MEN1 (0.46) | MTNR1AMTNR1BMEN1KMT2AMAPT | |
| SCHEMBL14709940 | 0.76 | NR4A2 (0.61) | PTGS2MEN1KMT2AALDH1A1TUBB4A | |
| SCHEMBL29033517 | 0.74 | MEN1 (0.63) | MTNR1AMTNR1BMEN1KMT2AMAPT | |
| SCHEMBL23690433 | 0.73 | L3MBTL1 (0.55) | PDE4BMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178243-A | Preparation method and application of (hetero) aryl fused carbazole compound | 西南医科大学 | 2023-05-30 | — | — | CN | disclosed |