Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.40 |
| ▸ | GABRE | P78334 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22747549 | 0.85 | MTNR1A (0.53) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL29033496 | 0.85 | MTNR1A (0.53) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL29033517 | 0.81 | MEN1 (0.63) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL22747530 | 0.78 | KDM4E (0.47) | ALDH1A1MAPTMTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL22161378 | 0.76 | TUBB4A (0.49) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL29033495 | 0.76 | PTGS2 (0.46) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL16789343 | 0.76 | MEN1 (0.50) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL1877477 | 0.72 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL1877475 | 0.72 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL5369793 | 0.72 | PDE4B (0.45) | ALDH1A1GABRA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178243-B | Preparation method and application of (hetero) aryl fused carbazole compound | 西南医科大学 | 2024-11-22 | — | — | CN | disclosed |
| CN-116178243-A | Preparation method and application of (hetero) aryl fused carbazole compound | 西南医科大学 | 2023-05-30 | — | — | CN | disclosed |