SCHEMBL29033869

SCHEMBL29033869

CCCC(=O)CCC(C)(C)CO

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
HDAC3 O15379 4/20 0.35
HDAC1 Q13547 4/20 0.35
HDAC2 Q92769 4/20 0.35
HDAC8 Q9BY41 4/20 0.35
FFAR3 O14843 3/20 0.35
TSHR P16473 1/20 0.33
ALDH1A1 P00352 2/20 0.32
IAPP P10997 2/20 0.32
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
CTSD P07339 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3279459 0.88 FFAR1 (0.31)
SCHEMBL12326779 0.87 MAPT (0.38) CES2CES1HDAC3HDAC1HDAC2
SCHEMBL3280020 0.84 FFAR1 (0.33) MAPTKMT2A
SCHEMBL8897262 0.84 ALDH1A1 (0.38) CES2CES1HDAC3HDAC1HDAC2
SCHEMBL8897573 0.84 CES2 (0.38) CES2CES1HDAC3HDAC1HDAC2
SCHEMBL10014775 0.78 CES2 (0.41) CES2CES1HDAC3HDAC1HDAC2
SCHEMBL12055963 0.77
SCHEMBL8896602 0.77 KMT2A (0.45) CES2CES1TSHRALDH1A1MAPT
SCHEMBL3280296 0.76 FFAR1 (0.39) ALDH1A1MAPTKMT2A
SCHEMBL11564017 0.75 TDP1 (0.33) CES2CES1TSHRALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116440905-A Aldehyde hydrogenation Cu-based catalyst and preparation method and application thereof 中海油天津化工研究设计院有限公司 2023-07-18 CN disclosed