SCHEMBL8897573

SCHEMBL8897573

CCCC(=O)CCC(C)(C)CC

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
HDAC3 O15379 4/20 0.36
HDAC1 Q13547 4/20 0.36
HDAC2 Q92769 4/20 0.36
HDAC8 Q9BY41 4/20 0.36
FFAR3 O14843 3/20 0.36
TSHR P16473 1/20 0.35
ALDH1A1 P00352 3/20 0.33
IAPP P10997 2/20 0.32
KMT2A Q03164 2/20 0.32
MAPT P10636 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
CTSD P07339 1/20 0.31
MEN1 O00255 1/20 0.30
CYP1A2 P05177 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11564017 0.93 TDP1 (0.33) CES2CES1TSHRALDH1A1KMT2A
SCHEMBL5705354 0.90 ALDH1A1 (0.32) ALDH1A1KMT2AMAPTMEN1CYP1A2
SCHEMBL8897262 0.86 ALDH1A1 (0.38) CES2CES1HDAC3HDAC1HDAC2
SCHEMBL29033869 0.84 CES2 (0.36) CES2CES1HDAC3HDAC1HDAC2
SCHEMBL27511799 0.83 TDP1 (0.43) FFAR3ALDH1A1IAPPKMT2AMEN1
SCHEMBL8897417 0.83 KMT2A (0.55) CES2CES1TSHRALDH1A1KMT2A
SCHEMBL8897919 0.83 KMT2A (0.45) CES2CES1TSHRALDH1A1KMT2A
SCHEMBL23380020 0.82
SCHEMBL10014775 0.80 CES2 (0.41) CES2CES1HDAC3HDAC1HDAC2
SCHEMBL8896602 0.79 KMT2A (0.45) CES2CES1TSHRALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0531715-B1 Process for producing alcohols and ketones SUMITOMO CHEMICAL CO (JP) 1997-11-05 EP disclosed
US-5426237-A Oxidation of straight, branched or cyclic alkanes and benzene derivatives in presence of transition metal catalyst and aldehyde SUMITOMO CHEMICAL CO., LTD. (JP) 1995-06-20 US disclosed
EP-0531715-A1 Process for producing alcohols and ketones SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-03-17 EP disclosed