Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | PHGDH | O43175 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29033888 | 0.91 | PHGDH (0.45) | PHGDHMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL29033882 | 0.88 | MAPT (0.54) | NPC1MAPTRAB9APHGDHMEN1 | |
| SCHEMBL29033886 | 0.85 | PRKD1 (0.48) | PHGDHMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL29033887 | 0.82 | BCHE (0.48) | BCHEACHENPC1MAPTRAB9A | |
| SCHEMBL29033901 | 0.82 | RAF1 (0.47) | MAPTPHGDHPRKD1KDRTHRB | |
| SCHEMBL29033909 | 0.78 | RAB9A (0.55) | NPC1MAPTRAB9APHGDHMEN1 | |
| SCHEMBL15425110 | 0.78 | MKNK1 (0.64) | NPC1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL25305249 | 0.77 | MAPT (0.65) | BCHEACHENPC1MAPTRAB9A | |
| SCHEMBL26915286 | 0.75 | RARB (0.50) | NPC1MAPTRAB9APRKD1POLB | |
| SCHEMBL26915302 | 0.74 | MAPT (0.50) | NPC1MAPTRAB9APRKD1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114394934-B | Pyrazole benzamide compound as well as preparation method and application thereof | 苏州大学 | 2023-06-13 | — | — | CN | disclosed |
| CN-114394934-A | Pyrazole benzamide compound and preparation method and application thereof | 苏州大学 | 2022-04-26 | — | — | CN | disclosed |