Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.55 |
| ▸ | NPC1 | O15118 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29033886 | 0.93 | PRKD1 (0.48) | MAPK1MEN1KMT2AROCK1ROCK2 | |
| SCHEMBL29033882 | 0.91 | MAPT (0.54) | RAB9ANPC1MAPTMAPK1CSNK2A2 | |
| SCHEMBL29033888 | 0.88 | PHGDH (0.45) | MAPK1MEN1KMT2AROCK1ROCK2 | |
| SCHEMBL29033894 | 0.83 | MAPT (0.53) | RAB9ANPC1MAPTMAPK1KDM4E | |
| SCHEMBL25307575 | 0.79 | MAPT (0.54) | RAB9ANPC1MAPTMAPK1CSNK2A2 | |
| SCHEMBL29033874 | 0.78 | BCHE (0.48) | RAB9ANPC1MAPTMAPK1ALDH1A1 | |
| SCHEMBL28354065 | 0.77 | TAS1R3 (0.70) | RAB9ANPC1TAS1R3TAS1R1HPGD | |
| SCHEMBL16199794 | 0.76 | RAB9A (0.75) | RAB9ANPC1MAPTMAPK1CSNK2A2 | |
| SCHEMBL20181593 | 0.75 | MAPT (0.58) | RAB9ANPC1MAPTMAPK1ALDH1A1 | |
| SCHEMBL936452 | 0.75 | PRKD1 (0.74) | PRKD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114394934-B | Pyrazole benzamide compound as well as preparation method and application thereof | 苏州大学 | 2023-06-13 | — | — | CN | disclosed |
| CN-114394934-A | Pyrazole benzamide compound and preparation method and application thereof | 苏州大学 | 2022-04-26 | — | — | CN | disclosed |