Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | PRKG1 | Q13976 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | PRKCG | P05129 | 2/20 | 0.46 |
| ▸ | PRKACA | P17612 | 2/20 | 0.46 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29033909 | 0.91 | RAB9A (0.55) | MAPTNPC1RAB9AMAPK1CSNK2A2 | |
| SCHEMBL29033888 | 0.89 | PHGDH (0.45) | MAPK1ROCK1ROCK2PRKG1CYP2C9 | |
| SCHEMBL29033874 | 0.88 | BCHE (0.48) | MAPTNPC1RAB9AMAPK1ALDH1A1 | |
| SCHEMBL29033886 | 0.83 | PRKD1 (0.48) | MAPK1ROCK1ROCK2PRKG1CYP2C9 | |
| SCHEMBL29033894 | 0.82 | MAPT (0.53) | MAPTNPC1RAB9AMAPK1ROCK1 | |
| SCHEMBL29033901 | 0.80 | RAF1 (0.47) | MAPTPHGDHKDM4ENPSR1PRKD1 | |
| SCHEMBL1608422 | 0.80 | RAB9A (0.84) | MAPTNPC1RAB9AMAPK1LMNA | |
| SCHEMBL25309254 | 0.79 | MAPT (0.53) | MAPTNPC1RAB9AMAPK1CSNK2A2 | |
| SCHEMBL28354065 | 0.76 | TAS1R3 (0.70) | NPC1RAB9ALMNAALDH1A1TAS1R3 | |
| SCHEMBL16199794 | 0.75 | RAB9A (0.75) | MAPTNPC1RAB9AMAPK1CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114394934-B | Pyrazole benzamide compound as well as preparation method and application thereof | 苏州大学 | 2023-06-13 | — | — | CN | disclosed |
| CN-114394934-A | Pyrazole benzamide compound and preparation method and application thereof | 苏州大学 | 2022-04-26 | — | — | CN | disclosed |