Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 2/20 | 0.47 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.46 |
| ▸ | PHGDH | O43175 | 1/20 | 0.44 |
| ▸ | PDE2A | O00408 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | ACR | P10323 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29033904 | 0.92 | RAF1 (0.57) | RAF1PRKD1PHGDHPDE2APPARG | |
| SCHEMBL29033887 | 0.91 | BCHE (0.48) | RAF1PRKD1PDE2APPARGPTGER4 | |
| SCHEMBL29033894 | 0.89 | MAPT (0.53) | RAF1PRKD1PHGDHPDE2AKDM4E | |
| SCHEMBL29033888 | 0.83 | PHGDH (0.45) | PRKD1PHGDHKDR | |
| SCHEMBL29033874 | 0.82 | BCHE (0.48) | PRKD1PHGDHPDE2AKDRMAPT | |
| SCHEMBL29033882 | 0.80 | MAPT (0.54) | PRKD1PHGDHKDM4EMAPTNPSR1 | |
| SCHEMBL25262291 | 0.80 | ABL1 (0.49) | RAF1PRKD1MAPT | |
| SCHEMBL29033886 | 0.77 | PRKD1 (0.48) | PRKD1PHGDHKDR | |
| SCHEMBL25308786 | 0.73 | MAPT (0.57) | RAF1PRKD1BRAFMAPT | |
| SCHEMBL29033909 | 0.71 | RAB9A (0.55) | PRKD1PHGDHKDM4EMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114394934-B | Pyrazole benzamide compound as well as preparation method and application thereof | 苏州大学 | 2023-06-13 | — | — | CN | disclosed |
| CN-114394934-A | Pyrazole benzamide compound and preparation method and application thereof | 苏州大学 | 2022-04-26 | — | — | CN | disclosed |