Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | PHGDH | O43175 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27987110 | 0.88 | POLB (0.52) | MAPTPOLBPHGDHALDH1A1LMNA | |
| SCHEMBL2323487 | 0.86 | ALDH1A1 (0.64) | MAPTPOLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL226006 | 0.83 | ALDH1A1 (0.57) | MAPTPOLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL29816440 | 0.83 | ALDH1A1 (0.57) | MAPTPOLBALDH1A1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6208562 | 0.82 | ALDH1A1 (0.56) | MAPTPOLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28393741 | 0.82 | MAPT (0.53) | MAPTPOLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL14982132 | 0.80 | ALDH1A1 (0.61) | MAPTPHGDHALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL19244150 | 0.79 | MAPT (0.51) | MAPTPOLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL325422 | 0.79 | NPC1 (0.70) | MAPTPOLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1286677 | 0.79 | ALDH1A1 (0.55) | MAPTPOLBALDH1A1NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116234800-A | Copper complexes for the treatment of neurodegenerative disorders | ALS治疗发展学会 | 2023-06-06 | — | — | CN | disclosed |