SCHEMBL226006

SCHEMBL226006

O=C(O)c1ccccc1N1CCOCC1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.57
KDM4E B2RXH2 4/20 0.57
GAA P10253 3/20 0.57
HPGD P15428 2/20 0.57
POLB P06746 2/20 0.55
MAPT P10636 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
PKM P14618 1/20 0.52
CYP1A2 P05177 3/20 0.51
CYP3A4 P08684 2/20 0.51
CYP2C19 P33261 2/20 0.51
LMNA P02545 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
AKR1C3 P42330 1/20 0.50
ALOX15 P16050 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
CHRNB2 P17787 1/20 0.49
CHRNA4 P43681 1/20 0.49
HSD17B10 Q99714 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29816440 1.00 ALDH1A1 (0.57) ALDH1A1KDM4EGAAHPGDPOLB
Hydrochloric Acid SCHEMBL6208562 0.98 ALDH1A1 (0.56) ALDH1A1KDM4EGAAHPGDPOLB
SCHEMBL28393741 0.87 MAPT (0.53) ALDH1A1KDM4EGAAHPGDPOLB
SCHEMBL8048603 0.87 ALDH1A1 (0.61) ALDH1A1POLBSMN1; SMN2MEN1KMT2A
SCHEMBL2323487 0.85 ALDH1A1 (0.64) ALDH1A1KDM4EGAAHPGDPOLB
SCHEMBL1286677 0.84 ALDH1A1 (0.55) ALDH1A1KDM4EHPGDPOLBMAPT
SCHEMBL29410870 0.84 NPC1 (0.70) ALDH1A1KDM4EGAAPOLBMAPT
SCHEMBL7757288 0.84 MAPT (0.50) ALDH1A1KDM4EGAAHPGDPOLB
SCHEMBL325422 0.84 NPC1 (0.70) ALDH1A1KDM4EGAAPOLBMAPT
SCHEMBL6608136 0.84 AKR1C3 (0.53) ALDH1A1KDM4EGAAHPGDPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119661473-A Method for synthesizing beta-sulfur trifluoromethyl alkylamine by olefin difunctional reaction 东北师范大学 2025-03-21 CN claimed
CN-118360608-B Copper-reducing additive for IC carrier plate and preparation method and use method thereof 深圳市板明科技股份有限公司 2024-08-13 CN claimed
CN-118360608-A Copper-reducing additive for IC carrier plate and preparation method and use method thereof 深圳市板明科技股份有限公司 2024-07-19 CN claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-105732889-A Photosensitive resin and synthetic method thereof 深圳市容大感光科技股份有限公司 2016-07-06 CN claimed
US-20050010045-A1 Reacting morpholine compound with a substituted benzene compound TIAN WEI (SE) 2005-01-13 US claimed
US-6689882-B2 REACTING A MORPHOLINE WITH A SUBSTITUTED BENZENE, WHEREIN MORPHOLINE IS USED AS A REACTANT AND AS THE ONLY ONE SOLVENT ASTRAZENECA AB (SE) 2004-02-10 US claimed
US-20030171581-A1 Process for the synthesis of morpholinylbenzenes ASTRAZENECA AB (SE) 2003-09-11 US claimed
EP-1286977-A1 A NEW PROCESS FOR THE SYNTHESIS OF MORPHOLINYLBENZENES AstraZeneca AB (SE) 2003-03-05 EP claimed
WO-2001087865-A1 A NEW PROCESS FOR THE SYNTHESIS OF MORPHOLINYLBENZENES ASTRAZENECA AB (SE) 2001-11-22 WO claimed
US-20250257041-A1 INDUCERS OF INTEGRATED STRESS RESPONSE TO TREAT CANCER THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2025-08-14 US disclosed
CN-120192315-A Echinococcosis-resistant medicine and preparation method and application thereof 新疆医科大学 2025-06-24 CN disclosed
US-12297209-B2 Benzodiazepine derivatives as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2025-05-13 US disclosed
US-12268694-B2 Combination pharmaceutical agents as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2025-04-08 US disclosed
EP-4526291-A1 INDUCERS OF INTEGRATED STRESS RESPONSE TO TREAT CANCER The Board of Regents of the University of Texas System (US) 2025-03-26 EP disclosed
WO-2000044730-A1 2,3,4,5-TETRAHYDRO-1H-[1,4]BENZODIAZEPINE-3-HYDROXAMIC ACID AS MATRIX METALLOPROTEINASE INHIBITORS AMERICAN CYANAMID COMPANY (US) 2000-08-03 WO disclosed
US-6071903-A ENZYME INHIBITORS OF MATRIX METALLOPROTEINASES (MMPS); ANTITUMOR,-CARCINOGENIC AND -ARTHRITIC AGENTS; OSTEOARTHRITIS; RHEUMATOID DISEASES; DEGENERATIVE CARTILAGE LOSS; LONG-ACTING, ORALLY BIOAVAILABLE NONPEPTIDE INHIBITORS AMERICAN CYANAMID COMPANY (US) 2000-06-06 US disclosed
US-5962440-A ANTICHOLESTEROL AGENT BRISTOL-MYERS SQUIBB COMPANY (US) 1999-10-05 US disclosed
WO-1999037625-A1 2,3,4,5-TETRAHYDRO-1H-[1,4]-BENZODIAZEPINE-3-HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASE INHIBITORS AMERICAN CYANAMID COMPANY (US) 1999-07-29 WO disclosed
WO-1999021564-A1 CYCLIC PHOSPHONATE ESTER INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN AND METHOD BRISTOL-MYERS SQUIBB COMPANY (US) 1999-05-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250257041-A1 INDUCERS OF INTEGRATED STRESS RESPONSE TO TREAT CANCER DDIT3, ATF4, EIF2AK3 ALDH1A1 4205/4885KDM4E 3125/4885GAA 3353/4885
US-12297209-B2 Benzodiazepine derivatives as RSV inhibitors GABRA5, GABRA1, GABBR2 ALDH1A1 621/4885KDM4E 1198/4885GAA 1755/4885
US-20030171581-A1 Process for the synthesis of morpholinylbenzenes CYP1B1, TBCB, MAP1B ALDH1A1 1548/4885KDM4E 2640/4885GAA 2462/4885
US-12268694-B2 Combination pharmaceutical agents as RSV inhibitors ACE, ACE2, SPCS3 ALDH1A1 4172/4885KDM4E 4059/4885GAA 1366/4885
US-20050010045-A1 Reacting morpholine compound with a substituted benzene compound CYP1B1, MYB, MYBBP1A ALDH1A1 1944/4885KDM4E 2799/4885GAA 2552/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.