SCHEMBL28393741

SCHEMBL28393741

O=C(c1ccccc1N1CCOCC1)c1ccccc1N1CCOCC1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.53
POLB P06746 1/20 0.53
AKR1C3 P42330 2/20 0.51
ALDH1A1 P00352 5/20 0.51
KDM4E B2RXH2 2/20 0.51
LMNA P02545 1/20 0.51
NPC1 O15118 4/20 0.50
SMN1; SMN2 Q16637 4/20 0.50
HPGD P15428 3/20 0.50
CYP1A2 P05177 3/20 0.50
RAB9A P51151 3/20 0.50
CYP3A4 P08684 2/20 0.50
CYP2C19 P33261 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
TP53 P04637 1/20 0.50
ALOX15 P16050 1/20 0.50
TSHR P16473 1/20 0.50
MAPK1 P28482 1/20 0.50
CASP1 P29466 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2323487 0.90 ALDH1A1 (0.64) MAPTPOLBAKR1C3ALDH1A1KDM4E
SCHEMBL29816440 0.87 ALDH1A1 (0.57) MAPTPOLBAKR1C3ALDH1A1KDM4E
SCHEMBL226006 0.87 ALDH1A1 (0.57) MAPTPOLBAKR1C3ALDH1A1KDM4E
SCHEMBL6608136 0.86 AKR1C3 (0.53) MAPTPOLBAKR1C3ALDH1A1KDM4E
SCHEMBL29410870 0.86 NPC1 (0.70) MAPTPOLBAKR1C3ALDH1A1KDM4E
Hydrochloric Acid SCHEMBL6208562 0.86 ALDH1A1 (0.56) MAPTPOLBAKR1C3ALDH1A1KDM4E
SCHEMBL325422 0.86 NPC1 (0.70) MAPTPOLBAKR1C3ALDH1A1KDM4E
SCHEMBL1286677 0.86 ALDH1A1 (0.55) MAPTPOLBAKR1C3ALDH1A1KDM4E
SCHEMBL7757288 0.86 MAPT (0.50) MAPTPOLBAKR1C3ALDH1A1KDM4E
SCHEMBL7757274 0.84 RAB9A (0.49) MAPTPOLBAKR1C3ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113166341-A Curable heat seal adhesive for bonding polymers 阿科玛法国公司 2021-07-23 CN disclosed
CN-107041155-B Optical fiber ribbon, method for producing optical fiber ribbon, and ultraviolet-curable resin composition for forming connection portion of intermittent fixed optical fiber ribbon 株式会社藤仓 2020-05-19 CN disclosed