Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 2/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027058 | 0.78 | AOC3 (0.44) | AOC3NPC1RAB9ASLC6A3SLC6A4 | |
| SCHEMBL13266816 | 0.70 | SMN1; SMN2 (0.42) | AOC3NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL73543 | 0.70 | AOC3 (0.47) | AOC3NPC1RAB9ASLC6A3SLC6A4 | |
| SCHEMBL29473571 | 0.69 | SLC6A4 (0.51) | SLC6A3SLC6A4KDM4E | |
| SCHEMBL1176147 | 0.69 | SLC6A4 (0.51) | SLC6A3SLC6A4KDM4E | |
| SCHEMBL1176145 | 0.69 | SLC6A4 (0.51) | SLC6A3SLC6A4KDM4E | |
| SCHEMBL28550307 | 0.69 | AOC3 (0.42) | AOC3NPC1RAB9ASLC6A3SLC6A4 | |
| SCHEMBL9704857 | 0.69 | DRD2 (0.50) | SLC6A3SLC6A4 | |
| SCHEMBL7866443 | 0.68 | CHRNB2 (0.41) | AOC3NPC1RAB9ASLC6A3SLC6A4 | |
| SCHEMBL9775944 | 0.68 | AOC3 (0.38) | AOC3NPC1RAB9ASLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999214-B | Indole dihydrofuran ring derivative and preparation method and application thereof | 中山大学 | 2023-06-16 | — | — | CN | disclosed |