SCHEMBL29034751

SCHEMBL29034751

CN(C)c1cccc(C(F)(F)F)c1C=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACP1 P24666 1/20 0.36
MAPT P10636 3/20 0.35
GAA P10253 2/20 0.35
KDM4E B2RXH2 1/20 0.35
NFKB1 P19838 1/20 0.35
ERN1 O75460 1/20 0.35
CA2 P00918 1/20 0.34
ESR1 P03372 1/20 0.34
PDK2 Q15119 1/20 0.33
PIM1 P11309 1/20 0.33
PIM3 Q86V86 1/20 0.33
CTSS P25774 1/20 0.33
METAP1 P53582 1/20 0.33
TDP1 Q9NUW8 3/20 0.33
MAPK1 P28482 2/20 0.33
HTR6 P50406 2/20 0.33
TSHR P16473 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL989191 0.80 NFKB1 (0.44) GAAKDM4ENFKB1PIM1PIM3
SCHEMBL17866239 0.76 KCNH2 (0.44) MAPTGAAKDM4EERN1CA2
SCHEMBL8111349 0.76 ALDH1A1 (0.39) GAAKDM4ENFKB1PIM1PIM3
SCHEMBL30454780 0.74 ACP1 (0.46) ACP1MAPTGAAKDM4EESR1
SCHEMBL1768874 0.74 ACP1 (0.46) ACP1MAPTGAAKDM4EESR1
SCHEMBL8792701 0.73 ALDH1A1 (0.40) MAPTGAAKDM4ECA2TDP1
SCHEMBL163605 0.73 SLC22A12 (0.41) NFKB1ERN1PIM1PIM3TDP1
SCHEMBL6854167 0.73 NFKB1 (0.47) NFKB1ERN1PIM1PIM3TDP1
SCHEMBL28114013 0.73 NFKB1 (0.39) GAAKDM4ENFKB1CA2PIM1
SCHEMBL909840 0.72 MEN1 (0.61) MAPTKDM4ENFKB1PIM1PIM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116425685-A Synthesis method of oxaagoli sodium impurity 安徽联创生物医药股份有限公司 2023-07-14 CN disclosed