Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.44 |
| ▸ | MAT2A | P31153 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18921245 | 0.82 | KCNH2 (0.59) | KCNH2MAT2AMAPTGAAKDM4E | |
| SCHEMBL95708 | 0.78 | ERN1 (0.50) | KCNH2MAT2AERN1TDP1ALDH1A1 | |
| SCHEMBL8792701 | 0.78 | ALDH1A1 (0.40) | MAPTGAAKDM4ETDP1CA2 | |
| SCHEMBL1870889 | 0.77 | SMN1; SMN2 (0.37) | KCNH2MAT2AERN1TDP1ALDH1A1 | |
| SCHEMBL29951325 | 0.76 | ERN1 (0.41) | MAPTGAAKDM4EERN1TDP1 | |
| SCHEMBL29034751 | 0.76 | ACP1 (0.36) | MAPTGAAKDM4EERN1TDP1 | |
| SCHEMBL1427794 | 0.73 | ERN1 (0.44) | MAPTGAAKDM4EERN1CA2 | |
| SCHEMBL27800920 | 0.73 | PTGS2 (0.36) | GAAKDM4ETDP1ALDH1A1MEN1 | |
| SCHEMBL1663012 | 0.72 | ACHE (0.48) | KCNH2MAT2AERN1TDP1ALDH1A1 | |
| SCHEMBL31227003 | 0.72 | ACHE (0.48) | KCNH2MAT2AERN1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3237547-B1 | DIRECT DYES AND COMPOSITION COMPRISING THE DYES | KAO GERMANY GMBH (DE) | 2019-03-20 | — | — | EP | disclosed |
| US-10196520-B2 | Direct dyes and composition comprising the dyes | KAO GERMANY GMBH (DE) | 2019-02-05 | — | — | US | disclosed |
| US-20170362436-A1 | DIRECT DYES AND COMPOSITION COMPRISING THE DYES | KAO GERMANY GMBH (DE) | 2017-12-21 | — | — | US | disclosed |
| EP-3237547-A1 | DIRECT DYES AND COMPOSITION COMPRISING THE DYES | Kao Germany GmbH (DE) | 2017-11-01 | — | — | EP | disclosed |
| WO-2016102207-A1 | DIRECT DYES AND COMPOSITION COMPRISING THE DYES | KAO GERMANY GMBH (DE) | 2016-06-30 | — | — | WO | disclosed |
| EP-3037485-A1 | Direct dyes and composition comprising the dyes | Kao Germany GmbH (DE) | 2016-06-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10196520-B2 | Direct dyes and composition comprising the dyes | KRT18, TUBB4A, BRDT | KCNH2 225/4885MAT2A 3948/4885MAPT 271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.