Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5711752 | 0.86 | TDP1 (0.54) | TDP1LMNAL3MBTL1PIN1MEN1 | |
| SCHEMBL855858 | 0.79 | ALDH1A1 (0.54) | TDP1LMNAL3MBTL1PIN1MEN1 | |
| SCHEMBL29034853 | 0.78 | CYP3A4 (0.45) | TDP1LMNAL3MBTL1PIN1MEN1 | |
| SCHEMBL6959131 | 0.76 | TDP1 (0.48) | TDP1LMNAL3MBTL1PIN1MEN1 | |
| SCHEMBL11493984 | 0.73 | TDP1 (0.54) | TDP1LMNAL3MBTL1PIN1MEN1 | |
| SCHEMBL2805987 | 0.72 | LMNA (0.72) | TDP1LMNAL3MBTL1PIN1MEN1 | |
| SCHEMBL7329538 | 0.72 | TAS1R3 (0.51) | TDP1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL17901029 | 0.72 | LMNA (0.72) | TDP1LMNAL3MBTL1PIN1MEN1 | |
| SCHEMBL4237234 | 0.72 | TDP1 (0.53) | TDP1LMNAL3MBTL1PIN1MEN1 | |
| SCHEMBL9451277 | 0.71 | PPARG (0.59) | TDP1LMNAL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108472381-B | Compounds and therapeutic uses thereof | 森陶里治疗有限公司 | 2023-06-06 | — | — | CN | disclosed |