Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.51 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16934944 | 0.91 | ALDH1A1 (0.50) | TAS1R3TAS1R1TAS1R2PPARGPPARA | |
| SCHEMBL11495749 | 0.85 | KMT2A (0.47) | TAS1R3TAS1R1TAS1R2PPARGPPARA | |
| SCHEMBL7324340 | 0.84 | ALDH1A1 (0.61) | MTNR1AMTNR1BALDH1A1LMNAHPGD | |
| SCHEMBL3512767 | 0.84 | LDHA (0.59) | PPARGPPARAKMT2AALDH1A1LMNA | |
| SCHEMBL15140360 | 0.84 | PPARG (0.47) | PPARGPPARAKMT2AALDH1A1LMNA | |
| SCHEMBL5112826 | 0.84 | LMNA (0.61) | TAS1R3TAS1R1TAS1R2KMT2AHDAC3 | |
| SCHEMBL5711753 | 0.84 | PPARA (0.53) | PPARGPPARAKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL5711752 | 0.83 | TDP1 (0.54) | PPARGPPARAKMT2AMTNR1AMTNR1B | |
| SCHEMBL6712994 | 0.82 | RAB9A (0.48) | KMT2ALMNAHPGDMEN1L3MBTL1 | |
| SCHEMBL11662042 | 0.82 | PPARG (0.51) | PPARGPPARAKMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526708-B1 | Sulfonamide, preparation and use thereof as medicine and intermediate | HOFFMANN LA ROCHE (CH) | 2000-10-18 | — | — | EP | disclosed |
| EP-0526708-A1 | Sulfonamide, preparation and use thereof as medicine and intermediate | F. HOFFMANN-LA ROCHE AG (CH) | 1993-02-10 | — | — | EP | disclosed |