SCHEMBL29035587

SCHEMBL29035587

CCO[Si](COC(=O)CCC(=O)OC[Si](OCC)(OCC)c1ccccc1)(OCC)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.44
TOP2A P11388 3/20 0.43
CYP4F2 P78329 2/20 0.40
CYP4A11 Q02928 2/20 0.40
TSHR P16473 2/20 0.40
TDP1 Q9NUW8 1/20 0.39
PARP1 P09874 1/20 0.38
POLB P06746 2/20 0.37
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29028335 0.84 TDP1 (0.44) SMN1; SMN2TOP2ACYP4F2CYP4A11TSHR
SCHEMBL21066802 0.83 TDP1 (0.41) SMN1; SMN2TOP2ACYP4F2CYP4A11TSHR
SCHEMBL28409149 0.82 TDP1 (0.41) SMN1; SMN2TOP2ATDP1POLBKDM4E
SCHEMBL237184 0.80 THRB (0.44) SMN1; SMN2TSHRALDH1A1MAPT
SCHEMBL236261 0.80 ALDH1A1 (0.41) SMN1; SMN2TSHRTDP1POLBKDM4E
SCHEMBL29028331 0.80 SMN1; SMN2 (0.40) SMN1; SMN2TOP2ATSHRTDP1ALDH1A1
SCHEMBL29053267 0.76 MAPT (0.42) SMN1; SMN2TSHRPOLBKDM4EALDH1A1
SCHEMBL22444885 0.75 LTA4H (0.31) KDM4EALDH1A1MAPT
SCHEMBL27754373 0.73 MAPT (0.34) SMN1; SMN2TOP2ATSHRPOLBKDM4E
SCHEMBL646940 0.73 LTA4H (0.34) SMN1; SMN2TSHRKDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109716491-B Method for manufacturing field effect transistor and method for manufacturing wireless communication device 东丽株式会社 2023-06-09 CN disclosed