SCHEMBL29035888

SCHEMBL29035888

Cc1cccc(C(=S)S)c1Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.39
TAS1R3 Q7RTX0 1/20 0.39
TAS1R1 Q7RTX1 1/20 0.39
TAS1R2 Q8TE23 1/20 0.39
GAA P10253 3/20 0.36
ALDH1A1 P00352 6/20 0.36
KDM4E B2RXH2 2/20 0.35
HPGD P15428 1/20 0.35
HSD17B10 Q99714 1/20 0.35
MAPT P10636 3/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
ENPP3 O14638 1/20 0.33
ALPL P05186 1/20 0.33
XIAP P98170 1/20 0.33
NPC1 O15118 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33
MYC P01106 1/20 0.32
POLB P06746 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8175043 0.78 TRPA1 (0.44) TAS1R3TAS1R1TAS1R2ALDH1A1KDM4E
SCHEMBL5426379 0.78 TSHR (0.43) GAAALDH1A1KDM4EHPGDMAPT
SCHEMBL16961109 0.76 ALDH1A1 (0.43) P2RX7TAS1R3TAS1R1TAS1R2ALDH1A1
SCHEMBL16958984 0.76 P2RX7 (0.41) P2RX7TAS1R3TAS1R1TAS1R2ALDH1A1
SCHEMBL23070440 0.74 KMT2A (0.48) P2RX7TAS1R3TAS1R1TAS1R2ALDH1A1
SCHEMBL16951975 0.74 P2RX7 (0.41) P2RX7TAS1R3TAS1R1TAS1R2ALDH1A1
SCHEMBL2963108 0.72 P2RX7 (0.46) P2RX7TAS1R3TAS1R1TAS1R2ALDH1A1
SCHEMBL306828 0.72 TSHR (0.63) P2RX7TAS1R3TAS1R1TAS1R2ALDH1A1
SCHEMBL697613 0.72 TAS1R3 (0.46) P2RX7TAS1R3TAS1R1TAS1R2ALDH1A1
SCHEMBL144551 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112533990-B Rubber composition, vulcanized rubber, and molded article of the vulcanized rubber 电化株式会社 2023-07-21 CN disclosed