Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.39 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyanide SCHEMBL22130315 | 0.95 | KDM4E (0.57) | KDM4EALDH1A1MAPK1NOTUMMAOB | |
| SCHEMBL27746116 | 0.83 | KDM4E (0.62) | KDM4EALDH1A1MAPK1NOTUMKMT2A | |
| SCHEMBL27725316 | 0.83 | KDM4E (0.62) | KDM4EALDH1A1MAPK1NOTUMKMT2A | |
| SCHEMBL11410050 | 0.80 | KDM4E (0.72) | KDM4EALDH1A1MAPK1NOTUMKMT2A | |
| SCHEMBL10653293 | 0.80 | KDM4E (0.72) | KDM4EALDH1A1MAPK1NOTUMKMT2A | |
| SCHEMBL4341894 | 0.79 | NOTUM (0.78) | KDM4EALDH1A1MAPK1NOTUMKMT2A | |
| SCHEMBL19979604 | 0.78 | KDM4E (0.70) | KDM4EALDH1A1MAPK1NOTUMKMT2A | |
| SCHEMBL98459 | 0.77 | ALDH1A1 (1.00) | KDM4EALDH1A1MAPK1NOTUMKMT2A | |
| SCHEMBL13221930 | 0.77 | ALDH1A1 (0.68) | KDM4EALDH1A1MAPK1NOTUMKMT2A | |
| SCHEMBL16549641 | 0.74 | KDM4E (0.64) | KDM4EALDH1A1MAPK1NOTUMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232070-A | Quinolinone alkaloid derivative containing acylhydrazone group on 1-site nitrogen atom and preparation method and application thereof | 太原理工大学 | 2022-10-25 | — | — | CN | claimed |
| CN-115232070-A | Quinolinone alkaloid derivative containing acylhydrazone group on 1-site nitrogen atom and preparation method and application thereof | 太原理工大学 | 2022-10-25 | — | — | CN | disclosed |