Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30534551 | 1.00 | HTR6 (0.40) | HTR6DNM1CXCR4MAPTBCHE | |
| SCHEMBL30534500 | 0.86 | MEN1 (0.44) | MAPTACHEMEN1KMT2A | |
| SCHEMBL29036153 | 0.86 | MEN1 (0.44) | MAPTACHEMEN1KMT2A | |
| SCHEMBL29036154 | 0.86 | CHRM2 (0.48) | DNM1ACHE | |
| SCHEMBL30534535 | 0.86 | CHRM2 (0.48) | DNM1ACHE | |
| SCHEMBL30534557 | 0.81 | BRD4 (0.43) | MAPTKDM4EMAPK1MEN1KMT2A | |
| SCHEMBL29036155 | 0.78 | PRMT6 (0.34) | — | |
| SCHEMBL29036158 | 0.74 | MAPT (0.42) | MAPTBCHEKDM4EKMT2A | |
| SCHEMBL30534501 | 0.74 | MAPT (0.42) | MAPTBCHEKDM4EKMT2A | |
| SCHEMBL29036163 | 0.72 | SLC6A2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116462686-A | 4-aryl (methyl) group-1, 4-benzoxazine imidazoline compound and preparation method and application thereof | 湖南科技大学 | 2023-07-21 | — | — | CN | disclosed |