Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29036154 | 1.00 | CHRM2 (0.48) | CHRM2ACHECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29036153 | 0.86 | MEN1 (0.44) | CHRM2ACHEDRD4 | |
| SCHEMBL30534500 | 0.86 | MEN1 (0.44) | CHRM2ACHEDRD4 | |
| SCHEMBL29036152 | 0.86 | HTR6 (0.40) | ACHEDNM1 | |
| SCHEMBL30534551 | 0.86 | HTR6 (0.40) | ACHEDNM1 | |
| SCHEMBL30534554 | 0.81 | SIGMAR1 (0.45) | CYP1A2CYP2C19LMNA | |
| SCHEMBL29036176 | 0.81 | ICMT (0.41) | CYP1A2CYP2C19LMNA | |
| SCHEMBL30534545 | 0.81 | ICMT (0.41) | CYP1A2CYP2C19LMNA | |
| SCHEMBL29036155 | 0.75 | PRMT6 (0.34) | — | |
| SCHEMBL29036163 | 0.75 | SLC6A2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116462686-B | 4-Aryl (methyl) group-1, 4-benzoxazine imidazoline compound and preparation method and application thereof | 湖南科技大学 | 2024-12-13 | — | — | CN | disclosed |
| CN-116462686-A | 4-aryl (methyl) group-1, 4-benzoxazine imidazoline compound and preparation method and application thereof | 湖南科技大学 | 2023-07-21 | — | — | CN | disclosed |