Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL751533 | 0.86 | HCAR3 (0.62) | MAPTKMT2AALDH1A1SMN1; SMN2HCAR3 | |
| SCHEMBL17336716 | 0.86 | KMT2A (0.55) | MAPTKMT2AMAPK1ALDH1A1HTT | |
| SCHEMBL4497487 | 0.85 | VCAM1 (0.55) | MAPTKMT2AMAPK1ALDH1A1HTT | |
| SCHEMBL753425 | 0.83 | KMT2A (0.72) | MAPTKMT2AMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL23517982 | 0.83 | KMT2A (0.45) | MAPTKMT2AMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14740824 | 0.82 | KMT2A (0.45) | MAPTKMT2AMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5868984 | 0.82 | HCAR3 (0.55) | MAPTKMT2AMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8231247 | 0.82 | ALDH1A1 (0.58) | MAPTKMT2AMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31365089 | 0.82 | ALDH1A1 (0.58) | MAPTKMT2AMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8469198 | 0.81 | KCNMA1 (0.50) | MAPTKMT2AMAPK1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116410189-B | Pyrimido pyridine compound and medicinal composition and application thereof | 中国科学院上海药物研究所 | 2024-08-06 | — | — | CN | disclosed |
| CN-116410189-A | Pyrimido pyridine compound and medicinal composition and application thereof | 中国科学院上海药物研究所 | 2023-07-11 | — | — | CN | disclosed |