SCHEMBL29036799

SCHEMBL29036799

Oc1ccc(CCN2CCc3ccccc3C2)nc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 5/20 0.50
HTR2A P28223 5/20 0.50
HTR7 P34969 5/20 0.50
DRD3 P35462 5/20 0.50
HTR2B P41595 5/20 0.50
DRD2 P14416 4/20 0.50
HRH1 P35367 3/20 0.48
HTR2C P28335 1/20 0.48
HDAC3 O15379 1/20 0.46
HDAC1 Q13547 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
NCOR2 Q9Y618 1/20 0.46
KDM4E B2RXH2 1/20 0.45
ALDH1A1 P00352 1/20 0.45
OPRM1 P35372 1/20 0.44
OPRD1 P41143 1/20 0.44
OPRK1 P41145 1/20 0.44
SLC6A4 P31645 2/20 0.44
PRMT5 O14744 1/20 0.43
WDR77 Q9BQA1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30503292 1.00 HTR1A (0.50) HTR1AHTR2AHTR7DRD3HTR2B
SCHEMBL29036767 0.77 HRH3 (0.51) HTR2AHTR2BHTR2C
SCHEMBL29036781 0.75 CYP1A2 (0.63)
SCHEMBL29036789 0.73 HRH3 (0.47) KDM4EALDH1A1
SCHEMBL12642689 0.72 HTR5A (0.65) HTR1AHTR2AHTR7DRD3HTR2B
SCHEMBL25223316 0.72 ACHE (0.45) HTR1AHTR2AHTR7DRD3HTR2B
SCHEMBL6512477 0.71 HRH3 (0.68) HTR1AHTR2AHTR7DRD3HTR2B
SCHEMBL25217531 0.71 HTR1A (0.44) HTR1AHTR2AHTR7DRD3HTR2B
SCHEMBL26192102 0.71 HDAC3 (0.42) HTR1AHTR2AHTR7DRD3HTR2B
SCHEMBL1193409 0.71 HDAC3 (0.59) HTR1AHTR2AHTR7DRD3HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116472267-A Butyrylcholinesterase reactivating agent 法兰西国由中央军队卫生服务局代表 2023-07-21 CN disclosed