Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290587 | 0.85 | TACR2 (0.32) | — | |
| SCHEMBL2893107 | 0.77 | TACR2 (0.40) | — | |
| SCHEMBL2893105 | 0.77 | TACR2 (0.40) | — | |
| SCHEMBL290368 | 0.75 | GHSR (0.35) | GHSRRET | |
| SCHEMBL2890519 | 0.74 | CTSC (0.48) | RET | |
| SCHEMBL2890517 | 0.74 | CTSC (0.48) | RET | |
| SCHEMBL27077969 | 0.71 | BDKRB1 (0.40) | — | |
| SCHEMBL27077971 | 0.71 | BDKRB1 (0.40) | — | |
| SCHEMBL28776778 | 0.69 | GHSR (0.35) | GHSRRET | |
| SCHEMBL16512497 | 0.68 | FAAH (0.51) | GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427445-A1 | SUBSTITUTED 1-CYANOETHYLHETEROCYCLYLCARBOXAMIDE COMPOUNDS 750 | AstraZeneca AB (SE) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128324-A1 | SUBSTITUTED 1-CYANOETHYLHETEROCYCLYLCARBOXAMIDE COMPOUNDS 750 | ASTRAZENECA AB (SE) | 2010-11-11 | — | — | WO | disclosed |