Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290369 | 0.85 | GHSR (0.32) | — | |
| SCHEMBL289267 | 0.77 | CTSC (0.43) | — | |
| SCHEMBL290581 | 0.73 | TACR2 (0.45) | TACR2 | |
| SCHEMBL290586 | 0.71 | CTSC (0.34) | TACR2 | |
| SCHEMBL288761 | 0.70 | CTSC (0.56) | TACR2 | |
| SCHEMBL289883 | 0.70 | CTSL (0.37) | TACR2 | |
| SCHEMBL17823082 | 0.64 | F2 (0.35) | — | |
| SCHEMBL16934688 | 0.64 | HPGD (0.34) | — | |
| SCHEMBL16498195 | 0.63 | FAAH (0.48) | — | |
| SCHEMBL16478069 | 0.62 | TACR2 (0.45) | TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427445-A1 | SUBSTITUTED 1-CYANOETHYLHETEROCYCLYLCARBOXAMIDE COMPOUNDS 750 | AstraZeneca AB (SE) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128324-A1 | SUBSTITUTED 1-CYANOETHYLHETEROCYCLYLCARBOXAMIDE COMPOUNDS 750 | ASTRAZENECA AB (SE) | 2010-11-11 | — | — | WO | disclosed |