Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7763213 | 0.81 | KMT2A (0.46) | LMNANPC1RAB9AESR1ESR2 | |
| Methyl 2-Methoxybenzoate SCHEMBL196037 | 0.77 | TSHR (0.69) | CTSDLMNANPC1ATMRAB9A | |
| SCHEMBL446339 | 0.77 | HPGD (0.59) | CTSDNPC1RAB9AESR1ESR2 | |
| Methyl 2-Methoxybenzoate SCHEMBL29702077 | 0.77 | TSHR (0.69) | CTSDLMNANPC1ATMRAB9A | |
| SCHEMBL8282169 | 0.77 | HDAC1 (0.65) | KDM4EHDAC8KMT2AHDAC1 | |
| SCHEMBL27875398 | 0.77 | CTSD (0.54) | CTSDLMNANPC1RAB9AESR1 | |
| Methyl 2-Methoxybenzoate SCHEMBL30744939 | 0.76 | MAPT (0.67) | CTSDLMNANPC1ATMRAB9A | |
| SCHEMBL873499 | 0.75 | TSHR (0.71) | CTSDLMNANPC1ATMRAB9A | |
| SCHEMBL28770702 | 0.75 | ALDH1A1 (0.61) | LMNANPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL29678391 | 0.75 | TSHR (0.71) | CTSDLMNANPC1ATMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118401531-A | Benzimidazole compound and medical application thereof | 中国科学院上海药物研究所 | 2024-07-26 | — | — | CN | disclosed |
| CN-115745929-B | Preparation method of prizepine succinate key intermediate | 山东四环药业股份有限公司 | 2024-01-19 | — | — | CN | disclosed |
| CN-116444544-A | Benzimidazole compound and medical application thereof | 中国科学院上海药物研究所 | 2023-07-18 | — | — | CN | disclosed |