SCHEMBL446339

SCHEMBL446339

COc1ccccc1C(=O)OC(=O)c1ccccc1OC

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.59
ALDH1A1 P00352 1/20 0.59
CTSD P07339 1/20 0.58
MAPT P10636 2/20 0.56
ESR1 P03372 1/20 0.56
ESR2 Q92731 1/20 0.56
XBP1 P17861 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
STAT3 P40763 1/20 0.55
GAA P10253 1/20 0.54
TSHR P16473 1/20 0.54
MAPK1 P28482 1/20 0.54
HSD17B10 Q99714 1/20 0.54
KMT2A Q03164 1/20 0.54
HTT P42858 2/20 0.53
NPC1 O15118 3/20 0.53
RAB9A P51151 2/20 0.53
ABCG2 Q9UNQ0 1/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
L3MBTL1 Q9Y468 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL125031 0.92 HPGD (0.56) HPGDALDH1A1CTSDMAPTESR1
SCHEMBL446340 0.91 SLC6A3 (0.60) HPGDALDH1A1CTSDMAPTESR1
SCHEMBL27290661 0.91 ALDH1A1 (0.65) HPGDALDH1A1CTSDMAPTESR1
SCHEMBL554492 0.90 HPGD (0.54) HPGDALDH1A1CTSDMAPTESR1
SCHEMBL7172322 0.90 HPGD (0.54) HPGDALDH1A1CTSDMAPTESR1
SCHEMBL717176 0.88 HPGD (0.57) HPGDALDH1A1CTSDMAPTESR1
SCHEMBL383183 0.87 HPGD (0.59) HPGDALDH1A1CTSDMAPTESR1
Methyl 2-Methoxybenzoate SCHEMBL196037 0.87 TSHR (0.69) HPGDALDH1A1CTSDMAPTNPSR1
SCHEMBL48968 0.87 HPGD (0.59) HPGDALDH1A1CTSDMAPTESR1
Methyl 2-Methoxybenzoate SCHEMBL29702077 0.87 TSHR (0.69) HPGDALDH1A1CTSDMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0067964-B1 PROCESS FOR THE PREPARATION OF 2-ISOSORBIDE NITRATE Heinrich Mack Nachf. (DE) 1985-04-03 EP claimed
US-4417065-A ACYLATION OF ISOSORBIDE AND ESTERIFICATION WITH NITRIC ACID HEINRICH MACK NACHF. CHEM.-PHARMAZEUTISCHE FABRIK (DE) 1983-11-22 US claimed
CN-120077502-A Electrolyte, electrochemical device, secondary battery, and lithium ion secondary battery 大金工业株式会社 2025-05-30 CN disclosed
CN-222709618-U Carbohydrazide preparation facilities 山东源泰新材料有限公司 2025-04-04 CN disclosed
CN-119497914-A Negative electrode, battery, and method for coating battery material 大金工业株式会社 2025-02-21 CN disclosed
CN-119487661-A Secondary battery 大金工业株式会社 2025-02-18 CN disclosed
CN-119422259-A Surface treatment agent for electrode material, positive electrode active material, current collecting foil, negative electrode active material, conductive auxiliary agent, electrode, battery, method for producing positive electrode active material, method for producing current collecting foil, method for producing negative electrode active material, method for producing conductive auxiliary agent, and method for producing electrode 大金工业株式会社 2025-02-11 CN disclosed
CN-119340518-A Lithium secondary battery and assembly 大金工业株式会社 2025-01-21 CN disclosed
CN-119340488-A Electrolyte, electrochemical device, lithium ion secondary battery and assembly 大金工业株式会社 2025-01-21 CN disclosed
CN-119318048-A Electrolyte and secondary battery using the same 大金工业株式会社 2025-01-14 CN disclosed
CN-119191950-A Asymmetric diaryl ketone compound and synthetic method thereof 海南大学 2024-12-27 CN disclosed
EP-2422005-A1 BIODEGRADABLE NONWOVEN FABRIC AND FIBER PRODUCT USING THE SAME JNC Corporation (JP) 2012-02-29 EP disclosed
WO-2010122806-A1 BIODEGRADABLE NONWOVEN FABRIC AND FIBER PRODUCT USING THE SAME CHISSO CORPORATION (JP) 2010-10-28 WO disclosed
WO-2007051255-A1 PROCESS FOR THE PREPARATION OF COMPOUNDS CONTAINING AN AZACYCLIC RING SYSTEM THE UNIVERSITY OF SYDNEY (AU) 2007-05-10 WO disclosed
US-6005116-A HAVE INHIBITION ACTIVITIES AGAINST TYPE A-MONOAMINE OXIDASE; TREATING OR PREVENTING DEPRESSION, PARKINSON'S DISEASE, ALZEHEIMER'S DEMENTIA, OR CEREBROVASCULAR DEMENTIA SANKYO COMPANY, LIMITED (JP) 1999-12-21 US disclosed
EP-0885891-A1 ISOXAZOLE DERIVATIVES SANKYO COMPANY LIMITED (JP) 1998-12-23 EP disclosed
US-5843983-A Diphenylethane compounds containing a saturated heterocyclic group, their preparation, and their therapeutic use SANKYO COMPANY, LIMITED (JP) 1998-12-01 US disclosed
EP-0790235-A1 Diaryl alkane derivatives containing an alicyclic group, their preparation and their therapeutic and prophylactic uses SANKYO COMPANY LIMITED (JP) 1997-08-20 EP disclosed
US-3970671-A XANTHENE, PRESSURE SENSITIVE KANZAKI PAPER MANUFACTURING CO., LTD. (JA) 1976-07-20 US disclosed
US-3947471-A CHROMOGENIC SUMITOMO CHEMICAL COMPANY, LTD. (JA) 1976-03-30 US disclosed