SCHEMBL29040562

SCHEMBL29040562

O=C(C=Cc1ccc2ccccc2c1)OCc1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B10 O60218 8/20 0.71
AKR1B1 P15121 8/20 0.71
TTR P02766 2/20 0.71
LMNA P02545 2/20 0.70
CA12 O43570 2/20 0.69
CA4 P22748 2/20 0.69
CA6 P23280 2/20 0.69
CA5A P35218 2/20 0.69
CA7 P43166 2/20 0.69
CA9 Q16790 2/20 0.69
CA14 Q9ULX7 2/20 0.69
CA5B Q9Y2D0 2/20 0.69
HCAR2 Q8TDS4 1/20 0.56
MAOB P27338 2/20 0.53
CYP3A4 P08684 2/20 0.53
ALOX15 P16050 2/20 0.53
ALOX12 P18054 2/20 0.53
MAPK1 P28482 2/20 0.53
HSD17B10 Q99714 2/20 0.53
ALDH1A1 P00352 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5593606 0.92 AKR1B10 (0.74) AKR1B10AKR1B1TTRLMNACA12
SCHEMBL5593610 0.92 AKR1B10 (0.74) AKR1B10AKR1B1TTRLMNACA12
SCHEMBL13552179 0.86 LMNA (0.93) AKR1B10AKR1B1TTRLMNACA12
SCHEMBL30449068 0.86 AKR1B10 (0.72) AKR1B10AKR1B1TTRLMNACA12
SCHEMBL20914998 0.86 AKR1B10 (0.72) AKR1B10AKR1B1TTRLMNACA12
Benzyl Cinnamate SCHEMBL43213 0.83 LMNA (1.00) AKR1B10AKR1B1TTRLMNACA12
Benzyl Cinnamate SCHEMBL43212 0.83 LMNA (1.00) AKR1B10AKR1B1TTRLMNACA12
Benzyl Cinnamate SCHEMBL1871854 0.83 LMNA (1.00) AKR1B10AKR1B1TTRLMNACA12
Benzyl Cinnamate SCHEMBL901152 0.83 LMNA (1.00) AKR1B10AKR1B1TTRLMNACA12
Benzyl Caffeate SCHEMBL1877243 0.83 AKR1B10 (1.00) AKR1B10AKR1B1TTRLMNACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116444370-A Preparation method of alpha, beta-unsaturated carboxylic acid derivative 大连理工常熟研究院有限公司 2023-07-18 CN disclosed