Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.56 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
| ▸ | NCF1 | P14598 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.48 |
| ▸ | ECE2 | P0DPD6 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1043719 | 0.98 | METAP2 (0.58) | METAP2PLAUNCF1ALDH1A1CYP1A2 | |
| SCHEMBL31157799 | 0.96 | METAP2 (0.56) | METAP2PLAUNCF1ALDH1A1CYP1A2 | |
| SCHEMBL29040599 | 0.96 | METAP2 (0.56) | METAP2PLAUNCF1ALDH1A1CYP1A2 | |
| SCHEMBL30457998 | 0.96 | METAP2 (0.56) | METAP2PLAUNCF1ALDH1A1CYP1A2 | |
| Phenol SCHEMBL28277519 | 0.89 | METAP2 (0.49) | METAP2PLAUNCF1ALDH1A1CYP1A2 | |
| Biphenyl SCHEMBL28203955 | 0.89 | METAP2 (0.49) | METAP2PLAUNCF1ALDH1A1CYP1A2 | |
| Phenol SCHEMBL28149601 | 0.89 | METAP2 (0.49) | METAP2PLAUNCF1ALDH1A1CYP1A2 | |
| SCHEMBL14337430 | 0.86 | MTNR1A (0.46) | METAP2PLAUNCF1ALDH1A1CYP1A2 | |
| SCHEMBL3227590 | 0.82 | METAP2 (0.57) | METAP2PLAUNCF1ALDH1A1CYP1A2 | |
| SCHEMBL4625590 | 0.80 | MEN1 (0.56) | METAP2PLAUNCF1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116444324-A | Application of organic lead salt, composition and preparation method thereof | 中国科学院上海有机化学研究所 | 2023-07-18 | — | — | CN | disclosed |