Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.57 |
| ▸ | PLAU | P00749 | 1/20 | 0.57 |
| ▸ | NCF1 | P14598 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | COMT | P21964 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4624293 | 0.87 | KDM4E (0.49) | METAP2PLAUNCF1ALOX12ALDH1A1 | |
| SCHEMBL4624601 | 0.84 | KMT2A (0.48) | METAP2PLAUNCF1ALOX12ALDH1A1 | |
| SCHEMBL1043719 | 0.84 | METAP2 (0.58) | METAP2PLAUNCF1ALOX12ALDH1A1 | |
| SCHEMBL4626479 | 0.83 | ALDH1A1 (0.47) | METAP2PLAUNCF1ALOX12ALDH1A1 | |
| SCHEMBL31157799 | 0.82 | METAP2 (0.56) | METAP2PLAUNCF1ALOX12ALDH1A1 | |
| SCHEMBL30457998 | 0.82 | METAP2 (0.56) | METAP2PLAUNCF1ALOX12ALDH1A1 | |
| SCHEMBL29040599 | 0.82 | METAP2 (0.56) | METAP2PLAUNCF1ALOX12ALDH1A1 | |
| SCHEMBL29040602 | 0.82 | METAP2 (0.56) | METAP2PLAUNCF1ALOX12ALDH1A1 | |
| SCHEMBL11817511 | 0.82 | KDM4E (0.56) | METAP2PLAUNCF1ALOX12ALDH1A1 | |
| SCHEMBL4626576 | 0.82 | MEN1 (0.56) | METAP2ALOX12ALDH1A1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318650-B2 | Bis(hydroxyquinoline) metal complexes as bleach catalysts | HENKEL AG & CO. KGAA (DE) | 2012-11-27 | — | — | US | disclosed |
| EP-2144880-B1 | BIS(HYDROXYQUINOLINE) METAL COMPLEXES AS BLEACH CATALYSTS | HENKEL AG & CO KGAA (DE) | 2012-05-30 | — | — | EP | disclosed |
| US-20100048447-A1 | BIS(HYDROXYQUINOLINE) METAL COMPLEXES AS BLEACH CATALYSTS | HENKEL AG & CO. KGAA (DE) | 2010-02-25 | — | — | US | disclosed |
| EP-2144880-A1 | BIS(HYDROXYQUINOLINE) METAL COMPLEXES AS BLEACH CATALYSTS | Henkel AG & Co. KGaA (DE) | 2010-01-20 | — | — | EP | disclosed |
| WO-2008135337-A1 | BIS(HYDROXYQUINOLINE) METAL COMPLEXES AS BLEACH CATALYSTS | HENKEL AG & CO. KGAA (DE) | 2008-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048447-A1 | BIS(HYDROXYQUINOLINE) METAL COMPLEXES AS BLEACH CATALYSTS | BLM, POLQ, HLCS | METAP2 1950/4885PLAU 3589/4885NCF1 1205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.