Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of 1,4-Butanediol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL11212324 | 0.85 | TSHR (0.42) | SLC34A1LMNAALDH1A1TSHRCAMK2A | |
| Phosphoric Acid SCHEMBL28807992 | 0.81 | SLC34A1 (0.38) | SMN1; SMN2GPR84FFAR1FFAR4SLC34A1 | |
| Phosphoric Acid SCHEMBL28051470 | 0.80 | ALDH1A1 (0.42) | SMN1; SMN2LMNAALDH1A1TSHRHSD17B10 | |
| Octacosanol SCHEMBL28716059 | 0.80 | LMNA (0.68) | SMN1; SMN2LMNAALDH1A1TSHRHSD17B10 | |
| Triacontanol SCHEMBL28823069 | 0.80 | LMNA (0.68) | SMN1; SMN2LMNAALDH1A1TSHRHSD17B10 | |
| Cetyl Alcohol SCHEMBL27924277 | 0.80 | LMNA (0.68) | SMN1; SMN2LMNAALDH1A1TSHRHSD17B10 | |
| Phosphoric Acid SCHEMBL28051595 | 0.79 | ALDH1A1 (0.43) | SLC34A1ALDH1A1TSHRFDPS | |
| Phosphoric Acid SCHEMBL8740021 | 0.77 | SLC34A1 (0.50) | SLC34A1LMNAALDH1A1TSHRCAMK2A | |
| Phosphoric Acid SCHEMBL9680822 | 0.77 | SLC34A1 (0.50) | SLC34A1LMNAALDH1A1TSHRCAMK2A | |
| Phosphoric Acid SCHEMBL31519804 | 0.77 | TSHR (0.42) | SLC34A1LMNAALDH1A1TSHRCAMK2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116515269-B | Superfine bamboo powder modified biodegradable polyester and preparation method thereof | 汕头市雷氏塑化科技有限公司 | 2023-09-01 | — | — | CN | disclosed |
| CN-116515269-A | Superfine bamboo powder modified biodegradable polyester and preparation method thereof | 汕头市雷氏塑化科技有限公司 | 2023-08-01 | — | — | CN | disclosed |