Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 11/20 | 0.51 |
| ▸ | PKLR | P30613 | 4/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.51 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29043227 | 0.88 | PIK3CD (0.52) | PKMPIK3CDPIK3CAPIK3CBMAPT | |
| SCHEMBL28919047 | 0.77 | PKM (0.54) | PKMPKLRMAPTRAB9AKMT2A | |
| SCHEMBL28919064 | 0.77 | HDAC3 (0.57) | PKMPKLR | |
| SCHEMBL28592201 | 0.74 | PKM (0.46) | PKMPKLRMAPTTP53RAB9A | |
| SCHEMBL13787617 | 0.72 | PIK3CD (0.74) | PKMPIK3CDPIK3CAPIK3CBMAPT | |
| SCHEMBL28919030 | 0.72 | HDAC3 (0.54) | PKMPKLRMAPTTP53KMT2A | |
| SCHEMBL28919018 | 0.72 | THRB (0.51) | PKMPKLRMAPTTP53KMT2A | |
| SCHEMBL2239830 | 0.71 | PKM (1.00) | PKMPKLRRAB9A | |
| SCHEMBL3015551 | 0.71 | AR (0.53) | PKMPKLRMAPTRAB9AKMT2A | |
| SCHEMBL28919074 | 0.71 | PKM (0.62) | PKMPKLRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521272-B | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2023-07-21 | — | — | CN | disclosed |