Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 11/20 | 0.54 |
| ▸ | PKLR | P30613 | 4/20 | 0.54 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28919038 | 0.87 | CNR1 (0.47) | PTGER1ALDH1A1SMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL28919018 | 0.84 | THRB (0.51) | PKMPKLRALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL3005812 | 0.81 | LMNA (0.67) | PKMPKLRALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL2949892 | 0.79 | CHRM4 (0.49) | PTGER1ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL3015815 | 0.79 | PKM (0.50) | PKMPKLRALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL3015551 | 0.77 | AR (0.53) | PKMPKLRALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL3011202 | 0.77 | ALDH1A1 (0.60) | PKMPKLRALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL29043239 | 0.77 | PKM (0.51) | PKMPKLRKMT2ALMNAMAPT | |
| SCHEMBL28919064 | 0.77 | HDAC3 (0.57) | PKMPKLR | |
| SCHEMBL3013174 | 0.76 | SMN1; SMN2 (0.62) | PKMPKLRALDH1A1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521272-B | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2023-07-21 | — | — | CN | disclosed |
| CN-115521272-A | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2022-12-27 | — | — | CN | disclosed |