Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | GAA | P10253 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | PTGDR2 | Q9Y5Y4 | 12/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.49 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29044463 | 0.89 | MAPT (0.45) | MAPTKMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL29044451 | 0.84 | MAPT (0.51) | MAPTKMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL29044481 | 0.84 | PTGDR2 (0.53) | MAPTKMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL30522187 | 0.84 | PTGDR2 (0.53) | MAPTKMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL4924576 | 0.78 | NPC1 (0.59) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29044464 | 0.77 | LMNA (0.62) | MAPTKMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL29044443 | 0.77 | ALDH1A1 (0.43) | MAPTKMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL8738730 | 0.75 | SMN1; SMN2 (0.74) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29044466 | 0.75 | MAPT (0.65) | MAPTKMT2AGAAMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6114152 | 0.74 | SMN1; SMN2 (0.72) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116531373-B | Thiazole compound, pharmaceutical composition and application thereof | 上海日馨医药科技股份有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-116531373-A | Thiazole compound, pharmaceutical composition and application thereof | 上海日馨医药科技股份有限公司 | 2023-08-04 | — | — | CN | disclosed |