Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | S100A4 | P26447 | 2/20 | 0.42 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | EIF4E | P06730 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9694041 | 0.84 | TDP1 (0.47) | TDP1ALDH1A1S100A4KMT2AMEN1 | |
| SCHEMBL13418991 | 0.81 | TDP1 (0.59) | TDP1ALDH1A1S100A4PTPRCKMT2A | |
| SCHEMBL29701218 | 0.78 | FBP1 (0.40) | TDP1ALDH1A1S100A4PTPRCKMT2A | |
| SCHEMBL30535903 | 0.76 | ALDH1A1 (0.74) | TDP1ALDH1A1S100A4PTPRCKMT2A | |
| SCHEMBL1287837 | 0.76 | ALDH1A1 (0.74) | TDP1ALDH1A1S100A4PTPRCKMT2A | |
| SCHEMBL6371400 | 0.76 | ALDH1A1 (0.53) | TDP1ALDH1A1S100A4PTPRCKMT2A | |
| SCHEMBL11617176 | 0.75 | TDP1 (0.57) | TDP1ALDH1A1S100A4PTPRCKMT2A | |
| SCHEMBL30520118 | 0.75 | S100A4 (0.47) | TDP1ALDH1A1S100A4PTPRCKMT2A | |
| SCHEMBL30987815 | 0.74 | ALDH1A1 (0.71) | TDP1ALDH1A1S100A4PTPRCKMT2A | |
| SCHEMBL29337140 | 0.74 | ALDH1A1 (0.71) | TDP1ALDH1A1S100A4PTPRCKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116528864-A | Heteroaryl carboxamide compounds | 安斯泰来制药株式会社 | 2023-08-01 | — | — | CN | disclosed |