SCHEMBL2904468

SCHEMBL2904468

Oc1ccc(Oc2ccnc(Oc3ccc(O)cc3)c2)cc1

nearest known ligand 0.54

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
ESR1 P03372 1/20 0.54
ESR2 Q92731 1/20 0.54
LTA4H P09960 6/20 0.47
NR1H2 P55055 1/20 0.47
BAX Q07812 1/20 0.47
LOXL2 Q9Y4K0 3/20 0.42
MAPK1 P28482 1/20 0.41
PARP10 Q53GL7 1/20 0.40
LOX P28300 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2906026 0.95 ESR2 (0.48) MEN1KMT2AESR1ESR2LTA4H
SCHEMBL2905418 0.87 CYP1A2 (0.39) MEN1KMT2AESR1ESR2LTA4H
SCHEMBL5686902 0.81 DRD1 (0.50) MEN1KMT2AESR1ESR2LTA4H
SCHEMBL2905433 0.78 MEN1 (0.54) MEN1KMT2AESR1ESR2LTA4H
SCHEMBL23076530 0.78 LMNA (0.42) MEN1KMT2AESR1ESR2LTA4H
SCHEMBL23337378 0.78 LTA4H (0.48) MEN1KMT2AESR1ESR2LTA4H
SCHEMBL5646966 0.78 NPC1 (0.56) MEN1KMT2AESR1ESR2
SCHEMBL4365227 0.75 KDM4E (0.49) MEN1KMT2AESR1ESR2LTA4H
SCHEMBL4363640 0.75 GCK (0.51) MEN1KMT2AESR1ESR2LTA4H
SCHEMBL4319106 0.74 MEN1 (0.70) MEN1KMT2AESR1ESR2LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1636209-B1 EPOXY COMPOUND AND CURED EPOXY RESIN PRODUCT SUMITOMO CHEMICAL CO (JP) 2010-08-11 EP disclosed
US-7279574-B2 Epoxy compound and cured epoxy resin product SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-10-09 US disclosed
US-20060159929-A1 Epoxy compound and cured epoxy resin product HITACHI, LTD. (JP) 2006-07-20 US disclosed