Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29045792 | 0.82 | KDM4E (0.63) | ALDH1A1KDM4EKMT2ASMN1; SMN2BACE1 | |
| SCHEMBL29045814 | 0.79 | ALDH1A1 (0.56) | ALDH1A1KDM4EKMT2AMEN1SGMS2 | |
| SCHEMBL29045848 | 0.79 | ALDH1A1 (0.59) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9938288 | 0.74 | KDM4E (0.54) | ALDH1A1KDM4EKMT2AMEN1TP53 | |
| SCHEMBL29985842 | 0.73 | KDM4E (0.68) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL29045812 | 0.72 | KDM4E (0.60) | ALDH1A1KDM4EKMT2AMEN1SGMS2 | |
| SCHEMBL29985588 | 0.72 | KDM4E (0.67) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| Carbamic Acid SCHEMBL5490106 | 0.70 | KMT2A (0.57) | ALDH1A1KDM4EKMT2AMEN1SGMS2 | |
| SCHEMBL2474305 | 0.70 | ALDH1A1 (0.88) | ALDH1A1KDM4EKMT2AMEN1PDE4A | |
| SCHEMBL29045835 | 0.69 | ALDH1A1 (0.55) | ALDH1A1KDM4EKMT2AMEN1SGMS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304502-A | FOXM1 inhibitor and preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2022-11-08 | — | — | CN | disclosed |