Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | XDH | P47989 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29045832 | 0.99 | KDM4E (0.63) | KDM4EALDH1A1TDP1CYP1A2CYP2D6 | |
| SCHEMBL12204181 | 0.94 | XDH (0.60) | KDM4EALDH1A1TDP1CYP1A2CYP2D6 | |
| SCHEMBL2352175 | 0.80 | KDM4E (0.69) | KDM4EALDH1A1TDP1CYP1A2CYP2D6 | |
| SCHEMBL29045812 | 0.79 | KDM4E (0.60) | KDM4EALDH1A1TDP1CYP1A2CYP2D6 | |
| SCHEMBL5701229 | 0.77 | KDM4E (0.60) | KDM4EALDH1A1TDP1CYP1A2CYP2D6 | |
| SCHEMBL2468950 | 0.76 | DRD2 (0.57) | KDM4EALDH1A1TDP1CYP1A2CYP2D6 | |
| SCHEMBL2470959 | 0.76 | KDM4E (0.63) | KDM4EALDH1A1TDP1CYP1A2CYP2D6 | |
| SCHEMBL23074698 | 0.75 | ALDH1A1 (0.70) | KDM4EALDH1A1TDP1CYP1A2CYP2D6 | |
| SCHEMBL12204135 | 0.75 | ALDH1A1 (0.70) | KDM4EALDH1A1TDP1CYP1A2CYP2D6 | |
| SCHEMBL1470185 | 0.75 | CHRNB2 (0.69) | ALDH1A1DRD2DRD4ADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304502-A | FOXM1 inhibitor and preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2022-11-08 | — | — | CN | disclosed |