SCHEMBL29047378

SCHEMBL29047378

COc1ccc(COCC2=C(OCc3ccc(OC)cc3)C(=O)CCC2)cc1

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAOB P27338 12/20 0.43
MAOA P21397 11/20 0.43
USP2 O75604 1/20 0.43
ALDH1A1 P00352 1/20 0.43
APP P05067 3/20 0.42
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
POLB P06746 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29047358 0.85 MAOB (0.52) MAOBMAOAALDH1A1NPC1RAB9A
SCHEMBL34413 0.73 IDO1 (0.67) MAOBALDH1A1APPSMN1; SMN2TDP1
SCHEMBL2374037 0.71 ALDH1A1 (0.45) MAOBMAOAUSP2ALDH1A1APP
SCHEMBL3857144 0.71 MAOA (0.81) MAOBMAOA
Methoxymethane SCHEMBL28823290 0.71 IDO1 (0.64) MAOBALDH1A1APPSMN1; SMN2TDP1
Bromide SCHEMBL28558295 0.71 IDO1 (0.64) MAOBALDH1A1APPSMN1; SMN2TDP1
Hydrochloric Acid SCHEMBL28912134 0.71 IDO1 (0.68) MAOBALDH1A1APPSMN1; SMN2TDP1
SCHEMBL1475481 0.71 IDO1 (0.64) MAOBALDH1A1APPSMN1; SMN2TDP1
Potassium SCHEMBL1477050 0.71 IDO1 (0.64) MAOBALDH1A1APPSMN1; SMN2TDP1
SCHEMBL6429953 0.69 LTA4H (0.69) MAOBAPPNPC1RAB9ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116535299-A SGLT2 inhibitor intermediate V-1 and application thereof 江苏万邦生化医药集团有限责任公司 2023-08-04 CN disclosed